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2014 Apr;59(4):1273-82

The ABCs of viral hepatitis that define biomarker signatures of acute viral hepatitis.

Duffy D, Mamdouh R, Laird M, Soneson C, Le Fouler L, El-Daly M, Casrouge A, Decalf J, Abbas A, Eldin NS, Fontes M, Abdel-Hamid M, Mohamed MK, Rafik M, Fontanet A, Albert ML.

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Journal of Immunology

J Immunol. 2014 Jan 15;192(2):641-8

HLA Micropolymorphisms Strongly Affect Peptide–MHC Multimer–Based Monitoring of Antigen-Specific CD8+ T Cell Responses.

van Buuren MM1, Dijkgraaf FE, Linnemann C, Toebes M, Chang CX, Mok JY, Nguyen M, van Esch WJ, Kvistborg P, Grotenbreg GM, Schumacher TN.



2013 Aug;63(2):105-12

CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients.

Ragab D, Laird M, Duffy D, Casrouge A, Mamdouh R, Abass A, Shenawy DE, Shebl AM, Elkashef WF, Zalata KR, Kamal M, Esmat G, Bonnard P, Fontanet A, Rafik M, Albert ML.

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PLOS Pathogens

2012 Jun;8(6):e1002759

Polyfunctional type-1, -2, and -17 CD8(+) T cell responses to apoptotic self-antigens correlate with the chronic evolution of hepatitis C virus infection.

Franceschini D, Del Porto P, Piconese S, Trella E, Accapezzato D, Paroli M, Morrone S, Piccolella E, Spada E, Mele A, Sidney J, Sette A, Barnaba V

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Analysis of IL28B Variants in an Egyptian Population Defines the 20 Kilobases Minimal Region Involved in Spontaneous Clearance of Hepatitis C Virus

Pedergnana V, Abdel-Hamid M, Guergnon J, Mohsen A, Le Fouler L, Theodorou I, Mohamed MK, Fontanet A, Plancoulaine S, Abel L.

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J Viral Hepat


HCV burden of infection in Egypt: results from a nationwide survey.

Guerra J, Garenne M, Mohamed MK, Fontanet A.

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Clin Exp Immunol


Discrimination of agonist and antagonist forms of CXCL10 in biological samples

Casrouge A, Bisiaux A, Stephen L, Schmolz M, Mapes J, Pfister C, Pol S, Mallet V, Albert ML.

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Interferon induced protein 10 remains a useful biomarker of treatment failure in patients stratified for the interleukin-28B rs12979860 Haplotype

Albert ML, Casrouge A, Chevaliez S, Hézode C, Rosa I, Renard P, Mallet V, Fontanet A, Pawlotsky JM, Pol S.

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Journal of Clinical Investigation


Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV.

Casrouge A, Decalf J, Ahloulay M, Lababidi C, Mansour H, Vallet-Pichard A, Mallet V, Mottez E, Mapes J, Fontanet A, Pol S, Albert ML.

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SPHINX-HepaCute joint workshop EASL conference, London April 9th 2014


Sphinx researchers to translate biomarker discoveries onto point of care technologies in new FP7 project, PoC-HCV

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